Emerging Therapeutic Strategies for Limbal Stem Cell Deficiency
نویسندگان
چکیده
منابع مشابه
Therapeutic Options for Patients with Bilateral Limbal Stem Cell Deficiency
Purpose: Live-related conjunctival-limbal allografting (Lr-CLAL), allogeneic cultivated limbal epithelial transplantation (allo-CLET). autologous cultivated oral mucosal epithelial transplantation (COMET) and Boston Type 1 Keratoprosthesis (Boston Kpro) are the four most widely performed procedures for patients with bilateral limbal stem cell deficiency (LSCD) with wet ocular surfaces. This stu...
متن کاملLimbal Stem Cell Deficiency: Current Treatment Options and Emerging Therapies
Severe ocular surface disease can result in limbal stem cell deficiency (LSCD), a condition leading to decreased visual acuity, photophobia, and ocular pain. To restore the ocular surface in advanced stem cell deficient corneas, an autologous or allogenic limbal stem cell transplantation is performed. In recent years, the risk of secondary LSCD due to removal of large limbal grafts has been sig...
متن کاملMinimal conjunctival limbal autograft for total limbal stem cell deficiency.
PURPOSE To report the results of one 60 degrees conjunctival limbal autograft (CLAU) combined with amniotic membrane (AM) transplantation for an eye with total limbal stem cell deficiency (LSCD). METHODS One eye of a patient with chronic total LSCD and symblepharon caused by chemical burn was subjected to symblepharon lysis, removal of pannus from corneal surface, AM transplantation to cover ...
متن کاملLong-term Outcome of Limbal Stem Cell Transplantation for the Management of Total Limbal Stem Cell Deficiency due to a Chemical Burn
Purpose: To evaluate the long-term outcome of limbal stem cell transplantation (LSCT) for the management of total limbal stem cell deficiency (LSCD) due to chemical burn in Labbafinejad Medical Center (LMC). Methods: Records of patients with a history of severe (i.e. grade III and IV) chemical burns, who were referred to LMC and underwent LSCT, were reviewed and data including demographic chara...
متن کاملAllo-limbal transplantation in patients with limbal stem cell deficiency.
AIM To report the outcome of a series of patients with stem cell deficiency who underwent allo-limbal transplantation and to describe a technique for this procedure. METHODS Six consecutive patients underwent allo-limbal stem cell transplantation. The primary diagnosis included alkali burn (n = 2), trachoma (n = 1), chronic rosacea blepharitis and kerato-conjunctivitis (n = 1), aniridia (n = ...
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ژورنال
عنوان ژورنال: Journal of Ophthalmology
سال: 2018
ISSN: 2090-004X,2090-0058
DOI: 10.1155/2018/7894647